This volume stems from the eighth international symposium and workshop entitled "Hematopoietic Stem Cells VIII" held hosted by the University of Tuebingen, Germany in the fall of 2011. The meeting was designed to bring ~30 leading scientists together to discuss the state-of-the-art in the field of hematopoietic stem cells. Topics reviewed in this volume include: differential requirements for Wnt and Notch signaling in hematopoietic versus thymic niches; hematopoietic stem cell expansion; TIM-3 as a therapeutic target for malignant stem cells in acute myelogenous leukemia; regulatory factors for hematopoietic stem cells; reprogramming factors; immune reconstitution and strategies for rebuilding of the immune system after haploidentical stem cell transplantation; zebrafish xenografts as a tool for in vivo studies on human cancer; enhancing engraftment of cord blood cells; current insights into neutrophil homeostasis; and molecular live cell bioimaging in stem cell research, among others.

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Lothar Kanz is a Professor in Hematology, Oncology und Immunology at the University of Tübingen, Tübingen, Germany.

Claudia Lengerke, M.D. is Head of the Laboratory for Developmental Biology, Division of Hematology and Oncology, at the University of Tuebingen Medical Center.

Willem E. Fibbe is a Professor at Leiden University Medical Center, Leiden, the Netherlands.

John E. Dick, PhD is a Senior Scientist in the Division of Cellular & Molecular Biology at Toronto General Research Institute (TGRI), University of Toronto, Toronto, Ontario, Canada.