{"product_id":"9781493997862","title":"Methods in Molecular Biology: Methods and Protocols","description":"\u003ch1\u003eMethods in Molecular Biology: Methods and Protocols\u003c\/h1\u003e \u003ch2\u003eRichard, Guy-Franck\u003c\/h2\u003e \u003cp\u003eThis detailed book contains techniques to explore the unusual properties of the peculiar microsatellites known as trinucleotide repeats.  Beginning with technical challenges raised by secondary structure-forming repeats and their propensity to contract and expand over time, the book continues with genetic screens in \u003ci\u003eSaccharomyces cerevisiae\u003c\/i\u003e, experimental systems to study trinucleotide repeat instability in human cells, dedicated experimental systems in appropriate cell types, as well as gene therapy approaches using the CRISPR-Cas family of endonucleases.  Written for the highly successful \u003ci\u003eMethods in Molecular Biology\u003c\/i\u003e series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. \u003c\/p\u003e\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\u003cdiv\u003eAuthoritative and practical, \u003ci\u003eTrinucleotide Repeats: Methods and Protocols\u003c\/i\u003e serves as avaluable aid to experts and newcomers alike who seek to investigate this fascinating and ever-expanding field of study.\u003c\/div\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2020-10-05\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9781493997862\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-4939-9784-8\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 286\u003c\/p\u003e ","brand":"Springer New York","offers":[{"title":"Default Title","offer_id":44806622642316,"sku":"9781493997862","price":107.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781493997862.jpg?v=1772848288","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781493997862","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}