Methods in Molecular Biology: Statistical and Computational Methods

Anisimova, Maria

This open access book addresses the challenge of analyzing and understanding the evolutionary dynamics of complex biological systems at the genomic level, and elaborates on some promising strategies that would bring us closer to uncovering of the vital relationships between genotype and phenotype. After a few educational primers, the book continues with sections on sequence homology and alignment, phylogenetic methods to study genome evolution, methodologies for evaluating selective pressures on genomic sequences as well as genomic evolution in light of protein domain architecture and transposable elements, population genomics and other omics, and discussions of current bottlenecks in handling and analyzing genomic data. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and expert implementation advice that lead to the best results. 

Details

Published by: Humana

Publication Date: 2019-07-06

Format: Hardcover

ISBN-13: 9781493990733

DOI: 10.1007/978-1-4939-9074-0

Dimensions: 254cm x178cm

Pages: 780