Methods in Molecular Biology: Methods and Protocols

Lai, Xin; Gupta, Shailendra K.; Vera, Julio

This volume details a collection of state-of-art methods including identification of novel ncRNAs and their targets, functional annotation and disease association in different biological contexts. Chapters guide readers through an overview of disease-specific ncRNAs, computational methods and workflows for ncRNA discovery, annotation based on high-throughput sequencing data, bioinformatics tools and databases for ncRNA analyses, network-based methods, and kinetic modelling of ncRNA-mediated gene regulation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Computational Biology of Non-Coding RNA: Methods and Protocols aims to provide a state-of-the-art collection of computational methodsand approaches that will be of value to researchers interested in ncRNA field.

Details

Published by: Humana

Publication Date: 2019-01-12

Format: Hardcover

ISBN-13: 9781493989812

DOI: 10.1007/978-1-4939-8982-9

Dimensions: 254cm x178cm

Pages: 451