{"product_id":"9781493987597","title":"Methods in Molecular Biology: Methods and Protocols","description":"\u003ch1\u003eMethods in Molecular Biology: Methods and Protocols\u003c\/h1\u003e \u003ch2\u003eFratti, Rutilio\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis book details multiple ways that \u003ci\u003es\u003c\/i\u003eoluble \u003ci\u003eN\u003c\/i\u003e-ethylmaleimide-sensitive factor \u003ci\u003ea\u003c\/i\u003ettachment protein \u003ci\u003ere\u003c\/i\u003eceptors( SNAREs) and their function are examined in the laboratory. The methods described in each chapter are described in detail so that novice as well as experienced researchers can explore the mechanisms of SNARE-mediated membrane fusion. Chapters guide readers through an overview of the basic properties of SNAREs, distribution and interaction with regulators of membrane fusion, activation of SNAREs in the priming stage by NSF\/Sec18 and a-SNAP\/Sec17, examining the structures and interactions of SNAREs, measuring the interactions of SNAREs, interactions of SNAREs, and post-translational modifications of SNAREs and how they affect function. Written in the highly successful \u003ci\u003eMethods in Molecular Biology \u003c\/i\u003eseries format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.\u003c\/p\u003e\n\nAuthoritative and cutting-edge, \u003ci\u003eSNAREs: Methods and Protocols \u003c\/i\u003eaims to be a valuable tool for all investigators interested in the field.\u003cp\u003e\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2018-10-14\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9781493987597\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-4939-8760-3\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 407\u003c\/p\u003e ","brand":"Springer New York","offers":[{"title":"Default Title","offer_id":45659284340876,"sku":"9781493987597","price":152.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781493987597.jpg?v=1772847461","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781493987597","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}