Methods in Molecular Biology: Methods and Protocols

Yokota, Toshifumi; Maruyama, Rika

This book presents a comprehensive collection of detailed state-of-the-art exon skipping and splices modulation protocols. Chapters detail 14 genetic diseases, AON-mediated therapies, and CRISPR/Cas9-mediated gene editing therapies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Exon Skipping and Inclusion Therapies: Methods and Protocols aims to help researchers initiate the development of next-generation therapies.

Details

Published by: Humana

Publication Date: 2018-09-01

Format: Hardcover

ISBN-13: 9781493986507

DOI: 10.1007/978-1-4939-8651-4

Dimensions: 254cm x178cm

Pages: 569