{"product_id":"9781493982325","title":"Methods in Molecular Biology: Methods and Protocols","description":"\u003ch1\u003eMethods in Molecular Biology: Methods and Protocols\u003c\/h1\u003e \u003ch2\u003eYokomori, Kyoko; Shirahige, Katsuhiko\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eThe volume provides comprehensive, state-of-the-art experimental techniques that are now available to dissect the molecular mechanisms of regulation and function of cohesin and the related factor condensin in vitro and in vivo across different model organisms, as well as in human cells. \u003ci\u003eCohesin and Condensin: Methods and Protocols \u003c\/i\u003eis divided into three parts: Part I explores various in vitro and in vivo systems used to study the fundamental mechanism of cohesin regulation in mitosis and meiosis; Part II summarizes experimental systems in a variety of organisms that are used to address interphase functions of cohesin and Nipbl in gene regulation and chromatin interaction, ribosome biogenesis and DNA repair, which contribute significantly to cohesion-associated disorders; Part III covers related condensin complex and describes techniques to study its role in mitosis and interphase. Written in the highly successful \u003ci\u003eMethods in Molecular Biology \u003c\/i\u003eseries format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.\u003cbr\u003e\u003cbr\u003eCutting-edge and thorough, \u003ci\u003eCohesin and Condensin: Methods and Protocols\u003c\/i\u003e is a valuable resource for diverse audiences with interests in the relationship between chromatin organization and genomic functions.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2018-07-06\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9781493982325\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-4939-6545-8\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 276\u003c\/p\u003e ","brand":"Springer New York","offers":[{"title":"Default Title","offer_id":46542906327180,"sku":"9781493982325","price":125.1,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781493982325.jpg?v=1772847035","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781493982325","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}