{"product_id":"9781493962921","title":"Methods in Molecular Biology: Methods and Protocols","description":"\u003ch1\u003eMethods in Molecular Biology: Methods and Protocols\u003c\/h1\u003e \u003ch2\u003eAlper, Hal S.\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eWith the ultimate goal of systematically and robustly defining the specific perturbations necessary to alter a cellular phenotype, systems metabolic engineering has the potential to lead to a complete cell model capable of simulating cell and metabolic function as well as predicting phenotypic response to changes in media, gene knockouts\/overexpressions, or the incorporation of heterologous pathways.  In \u003ci\u003eSystems Metabolic Engineering: Methods and Protocols\u003c\/i\u003e, experts in the field describe the methodologies and approaches in the area of systems metabolic engineering and provide a step-by-step guide for their implementation. Four major tenants of this approach are addressed, including modeling and simulation, multiplexed genome engineering, ‘omics technologies, and large data-set incorporation and synthesis, all elucidated through the use of model host organisms.  Written in the highly successful \u003ci\u003eMethods in Molecular Biology™\u003c\/i\u003e series format, chapters include introductions on their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003eComprehensive and cutting-edge, \u003ci\u003eSystems Metabolic Engineering: Methods and Protocols\u003c\/i\u003e serves as an ideal guide for metabolic engineers, molecular biologists, and microbiologists aiming to implement the most recent approaches available in the field. \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2017-04-30\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9781493962921\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-62703-299-5\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 474\u003c\/p\u003e ","brand":"Humana Press","offers":[{"title":"Default Title","offer_id":46542854127756,"sku":"9781493962921","price":116.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781493962921.jpg?v=1772845658","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781493962921","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}