{"product_id":"9781493962679","title":"Methods in Molecular Biology: Methods and Protocols","description":"\u003ch1\u003eMethods in Molecular Biology: Methods and Protocols\u003c\/h1\u003e \u003ch2\u003eBarnard, Lori; Aston, Kenneth I.\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eDeficiencies in sperm function are usually the result of spermatogenic defects. Spermatogenesis is a biologically complex and essential process during which spermatogonia undergo meiotic recombination, reduction of the genome to a haploid state, and extensive cellular modifications that result in a motile cell capable of traversing the female reproductive tract, withstanding various potential assaults to viability, and finally successfully fertilizing a mature oocyte to give rise to an embryo. Defects in any step of spermatogenesis or spermatogenesis can lead to male infertility, a disease that affects approximately 5-7% of the population. \u003ci\u003eSpermiogenesis and Spermatogenesis: Methods and Protocols\u003c\/i\u003e details protocols used in the study of spermatogenesis, clinical analytical protocols, and basic techniques used in clinical andrology laboratories, such as obtaining accurate results for a sperm count, and advanced procedures, such as genome-wide genetic study tools and evaluation of nuclear proteins. Written in the successful \u003ci\u003eMethods in Molecular Biology™\u003c\/i\u003e series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eAuthoritative and easily accessible, \u003ci\u003eSpermiogenesis and Spermatogenesis: Methods and Protocols\u003c\/i\u003e is unique in its breadth, and will be a useful reference for clinicians and researchers alike.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2016-08-23\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9781493962679\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-62703-038-0\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 554\u003c\/p\u003e ","brand":"Humana Press","offers":[{"title":"Default Title","offer_id":46542834794636,"sku":"9781493962679","price":143.1,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781493962679.jpg?v=1772845170","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781493962679","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}