{"product_id":"9781493961887","title":"Methods in Molecular Biology","description":"\u003ch1\u003eMethods in Molecular Biology\u003c\/h1\u003e \u003ch2\u003eYu, Bing; Hinchcliffe, Marcus\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eAs functional genomics has become one of the major focuses in molecular biology, the need for more sophisticated tools to assist in the identification of the functionality of undefined genes and the correlation of DNA variants with a particular phenotype has increased greatly.  \u003ci\u003eIn Silico Tools for Gene Discovery\u003c\/i\u003e collects many common and useful \u003ci\u003ein silico\u003c\/i\u003e tools available today.  The volume begins by investigating locus mapping information on linkage analysis, association mapping, integrative analysis, and exome analysis as well as tools for DNA marker selection, \u003ci\u003ein silico\u003c\/i\u003e PCR, and statistical analysis.  It continues with a section on gene discovery from a defined locus, including gene prioritization, knowledge tracking, and data mining, and concludes with several useful \u003ci\u003ein silico\u003c\/i\u003e tools presented for the functional characterization of genes, which include DNA sequencing analysis, variant characterization, as well as RNA and protein  analysis.  Written in the highly successful \u003ci\u003eMethods in Molecular Biology™\u003c\/i\u003e series format, chapters include introductions to their respective topics, step-by-step, readily reproducible protocols, and vital notes on troubleshooting and avoiding known pitfalls.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003eResourceful and easy to follow, \u003ci\u003eIn Silico Tools for Gene Discovery\u003c\/i\u003e seeks to facilitate scientists with further key research on locus mapping, to accelerate gene identification, and to help ascertain the functionality of DNA variation. \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2016-08-23\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9781493961887\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-61779-176-5\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 365\u003c\/p\u003e ","brand":"Humana Press","offers":[{"title":"Default Title","offer_id":46542840889484,"sku":"9781493961887","price":107.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781493961887.jpg?v=1772845586","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781493961887","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}