{"product_id":"9781493961313","title":"Methods in Molecular Biology: Methods and Protocols","description":"\u003ch1\u003eMethods in Molecular Biology: Methods and Protocols\u003c\/h1\u003e \u003ch2\u003eClarke, Charlotte H.; McCarthy, Diane L. Bankert\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eSELDI is distinct from other TOF-MS technologies in that it couples features of chromatography and mass spectrometry, facilitating analyte enrichment and sample cleanup on an array surface. In the growing field of proteomics, SELDI technology has been widely used for biomarker discovery and characterization in diverse applications including diagnostics, drug development, and basic research. SELDI-based biomarker studies can typically be divided into four phases: discovery, validation, purification and identification, and assay development. \u003ci\u003eSELDI-TOF Mass Spectrometry: Methods and Protocols\u003c\/i\u003e provides an overview of the current applications of SELDI-TOF MS (surface enhanced laser desorption\/ionization time-of-flight mass spectrometry), with an emphasis on study and experimental design, data analysis and interpretation, and assay development. Written in the highly successful \u003ci\u003eMethods in Molecular Biology™\u003c\/i\u003e series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eAuthoritative and accessible, \u003ci\u003eSELDI-TOF Mass Spectrometry: Methods and Protocols\u003c\/i\u003e will provide information on optimizing study design, experimental protocols, and data analysis and interpretation to yield robust biomarkers and biomarker assays, using examples from different disease areas.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2016-08-23\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9781493961313\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-61779-418-6\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 239\u003c\/p\u003e ","brand":"Humana Press","offers":[{"title":"Default Title","offer_id":46265639141516,"sku":"9781493961313","price":125.1,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781493961313.jpg?v=1770787142","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781493961313","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}