{"product_id":"9781493959716","title":"Methods in Molecular Biology","description":"\u003ch1\u003eMethods in Molecular Biology\u003c\/h1\u003e \u003ch2\u003eKohwi, Yoshinori; McMurray, Cynthia T.\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eTwo decades have passed since trinucleotide repeat expansion was first discovered in genes responsible for certain neurological diseases. Since then, new technologies have developed and innovative concepts have emerged, which may prove useful in devising therapeutic approaches to neurological diseases. Divided into six convenient sections, \u003ci\u003eTrinucleotide Repeat Protocols, Second Edition \u003c\/i\u003ecovers a wide range of topics such as an overview of trinucleotide repeat diseases, synaptic plasticity, embryonic stem (ES) cell-related protocols with a focus on HD, RNA-related protocols, and analysis of epigenetic modification in fragile X syndrome. \u003ci\u003e \u003c\/i\u003eThis edition focuses not only on direct analysis of trinucleotide repeat diseases but also on alternative approaches for the analysis of trinucleotide repeat diseases, with the hope that this will result in a better understanding of the mechanisms and future therapeutic prospects for treatment of these diseases. Written in the successful \u003ci\u003eMethods in Molecular Biology™\u003c\/i\u003e series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eAuthoritative and easily accessible, \u003ci\u003eTrinucleotide Repeat Protocols, Second Edition\u003c\/i\u003e seeks to serve researchers with its thorough methodologies on this expanding field.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2016-08-23\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9781493959716\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-62703-411-1\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 296\u003c\/p\u003e ","brand":"Humana Press","offers":[{"title":"Default Title","offer_id":46542838530188,"sku":"9781493959716","price":107.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781493959716.jpg?v=1772845427","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781493959716","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}