{"product_id":"9781493958276","title":"Methods in Molecular Biology: Methods and Protocols","description":"\u003ch1\u003eMethods in Molecular Biology: Methods and Protocols\u003c\/h1\u003e \u003ch2\u003eHobman, Tom C.; Duchaine, Thomas F.\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eWith the rapid proliferation of RNAi applications in basic and clinical sciences, the challenge has now become understanding how components of RNAi machinery function together in a regulated manner.  Argonaute proteins are the central effectors of RNAi and are highly conserved among eukaryotes and some archaebacteria. These RNA-binding proteins use small guide RNAs to silence expression of genes at the mRNA and DNA levels.  In \u003ci\u003eArgonaute Proteins: Methods and Protocols\u003c\/i\u003e, expert researchers in this burgeoning field provide detailed, up-to-date methods to study Argonaute protein functions and interactions in a wide variety of cell types ranging from yeast to mammalian systems, as well as \u003ci\u003ein vitro\u003c\/i\u003e.  Written in the highly successful \u003ci\u003eMethods in Molecular Biology™\u003c\/i\u003e series format, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003ePractical and authoritative, \u003ci\u003eArgonaute Proteins: Methods and Protocols\u003c\/i\u003e serves as a vital reference for both experienced and novice scientists approaching the vast complexities of RNAi research. \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2016-08-23\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9781493958276\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-61779-046-1\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 344\u003c\/p\u003e ","brand":"Humana Press","offers":[{"title":"Default Title","offer_id":46265641435276,"sku":"9781493958276","price":143.1,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781493958276.jpg?v=1770787239","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781493958276","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}