{"product_id":"9781493949670","title":"Methods in Molecular Biology: Methods and Protocols","description":"\u003ch1\u003eMethods in Molecular Biology: Methods and Protocols\u003c\/h1\u003e \u003ch2\u003eFilizola, Marta\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis detailed volume provides an overview of recent techniques employed in the field of G protein-coupled receptors (GPCRs) to screen for new drugs and to derive information about their receptor structure, dynamics, and function for the purpose of developing improved therapeutics. Owing to remarkable recent advances in the structural, biophysical and biochemical analyses of these receptors, as well as a growing body of evidence hinting at the possible relevance of allosteric modulators, biased agonists and oligomer-selective ligands as improved therapeutic agents, drug discovery for GPCRs has recently taken a completely new direction. For this book, expert contributors have shared their protocols and views on the impact of these methodologies on modern drug discovery. Written for the highly successful \u003ci\u003eMethods in Molecular Biology\u003c\/i\u003e series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.\u003c\/p\u003e\u003cp\u003ePractical and fully updated, \u003ci\u003eG Protein-Coupled Receptors in Drug Discovery: Methods and Protocols, Second Edition\u003c\/i\u003e serves as an ideal guide for a diverse audience from structural and molecular biologists to pharmacologists and drug designers who wish to explore this extensive class of key drug targets.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2018-02-21\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9781493949670\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-4939-2914-6\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 327\u003c\/p\u003e ","brand":"Springer New York","offers":[{"title":"Default Title","offer_id":46542831026316,"sku":"9781493949670","price":125.1,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781493949670.jpg?v=1772844958","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781493949670","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}