Protein Tyrosine Phosphatases in Cancer

Neel, Benjamin G.; Tonks, Nicholas K.

This book aims to bridge the gap in understanding how protein-tyrosine phosphatases (PTPs), which carry out the reverse reaction of tyrosine phosphorylation, feature in cancer cell biology. The expertly authored chapters will first review the general features of the PTP superfamily, including their overall structure and enzymological properties; use selected examples of individual PTP superfamily members, to illustrate emerging data on the role of PTPs in cancer; and will review the current status of PTP-based drug development efforts.

Details

Published by: Springer

Publication Date: 2016-08-05

Format: Hardcover

ISBN-13: 9781493936472

DOI: 10.1007/978-1-4939-3649-6

Dimensions: 235cm x155cm

Pages: 360