{"product_id":"9781493920525","title":"Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease","description":"\u003ch1\u003eReceptor Tyrosine Kinases: Structure, Functions and Role in Human Disease\u003c\/h1\u003e \u003ch2\u003eWheeler, Deric L.; Yarden, Yosef\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003ci\u003eReceptor Tyrosine Kinase: Structure, Functions and Role in Human Disease\u003c\/i\u003e, for the first time, systematically covers the shared structural and functional features of the RTK family. Receptor Tyrosine Kinases (RTKs) play critical roles in embryogenesis, normal physiology and several diseases. And over the last decade they have become the \u003ci\u003eNumber 1\u003c\/i\u003e targets of cancer drugs. To be able to conduct fundamental research or to attempt to develop pharmacological agents able to enhance or intercept them, it is essential first to understand the evolutionary origin of the 58 RTKs and their roles in invertebrates and in humans, as well as downstream signaling pathways. The assembly of chapters is written by experts and underscores commonalities between and among the RTKs. It is an ideal companion volume to \u003ci\u003eThe Receptor Tyrosine Kinase: Families and Subfamilies\u003c\/i\u003e, which proceeds, family by family through all of the specific subfamilies of RTKs, along with their unique landmarks.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2014-11-27\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9781493920525\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-4939-2053-2\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 440\u003c\/p\u003e ","brand":"Springer New York","offers":[{"title":"Default Title","offer_id":50150024183948,"sku":"9781493920525","price":152.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781493920525.jpg?v=1779581969","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781493920525","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}