{"product_id":"9781489994356","title":"Molecular Genetics of Pancreatic Cancer","description":"\u003ch1\u003eMolecular Genetics of Pancreatic Cancer\u003c\/h1\u003e \u003ch2\u003eSimeone, Diane M.; Maitra, Anirban\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003ePancreatic cancer is a formidable disease, and advances in early detection and improved therapeutics have been slow to come forth. With new advances in molecular genetics in the field of pancreatic tumorigenesis, it is an opportune time to use these recent discoveries to enhance our understanding of pancreatic cancer biology and to improve outcomes in patients.  \u003c\/p\u003e\u003cp\u003eIn this volume, leading experts in the field shed light on these findings describing the mutational landscape of pancreatic cancer, including new inroads into our understanding of familial pancreatic cancer, epidemiology, the biology of K-ras signaling, and the emerging contribution of epigenetic alterations to disease initiation and progression. The distinctive pancreatic cancer-stroma ecosystem as determined by the dynamic interplay of inflammation, hallmark mutations, EMT, and cancer stem cells is described, and implications of these interactions in the context of development of novel, personalized therapeutic options are explored.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2015-05-20\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9781489994356\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-4614-6549-2\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 235\u003c\/p\u003e ","brand":"Springer New York","offers":[{"title":"Default Title","offer_id":47408683614348,"sku":"9781489994356","price":107.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781489994356.jpg?v=1775833835","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781489994356","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}