Insertional Mutagenesis Strategies in Cancer Genetics

Dupuy, Adam J.; Largaespada, David A.

The goal of this work is summarize the contribution that insertional mutagenesis has made to our understanding of cancer. A variety of insertional mutagens are presented that have been used to study a variety of tumor types in several model organisms. In addition, the impact of insertional mutagenesis in several gene therapy trials is discussed along with strategies to avoid such complications in future clinical trials.

Details

Published by: Springer

Publication Date: 2014-10-07

Format: Paperback

ISBN-13: 9781489981349

DOI: 10.1007/978-1-4419-7656-7

Dimensions: 235cm x155cm

Pages: 200