{"product_id":"9781489927262","title":"Advances in Experimental Medicine and Biology: Proceedings of an International Symposium on the Pharmacology of Hormonal Polypeptides, held in Milan, Italy, September 14–16, 1967","description":"\u003ch1\u003eAdvances in Experimental Medicine and Biology: Proceedings of an International Symposium on the Pharmacology of Hormonal Polypeptides, held in Milan, Italy, September 14–16, 1967\u003c\/h1\u003e \u003ch2\u003eBack, Nathan\u003c\/h2\u003e \u003cp\u003eIt can be concluded (under the specific experimental procedures em­ ployed) that:- 1) HCG labelled with 1 - 2 atoms of radioactive iodine did not differ sig­ nificantly from the unlabelled hormone; 2) The ovary alone exhibited a capacity to affix specifically HCG; 3) The amount of radioactive material in the ovary was directly proport­ ional to the quantity of labelled HCG injected; 4) When the HCG present in the circulation is bound to an antiserum to HCG, the antigen-antibody complex is not concentrated by the ovary; 5) Circulating labelled HCG decreased to 50% within 30 minutes following a single intravenous injection; 6) There are four different phases of ovarian uptake of HCG, namely:­ the first phase, when there is only an inflow from the circulation and stor­ age mainly in the follicular envelopes; the second phase, when there is a greater inflow than outflow; the third phase, when the inflow is equal to the outflow; and the fourth period, when the outflow is bigger than the in­ flow. REFERENCES 1. Lunenfeld, B. and Eshkol, A. Vitamins and Hormones (1967) 25:165 2. Eshkol, A. In: Recent Research on Gonadotropbio Hormones, eds. E. T. Bell andJ. A. Loraine, Edinburgh, Livingstone (1967), p. 202. 3. Eshkol, A. and Lunenfeld, B. Proc. Tel-Hashomer Hosp. (1967) 6:4. ACKNOWLEOOMEN'IS This work was supported in part by a grant from the Population Council, N. Y. , U. S. A. andbyGrantNo.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2013-12-07\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9781489927262\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-4614-4612-5\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 660\u003c\/p\u003e ","brand":"Springer US","offers":[{"title":"Default Title","offer_id":47978051010700,"sku":"9781489927262","price":49.49,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781489927262.jpg?v=1777374930","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781489927262","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}