{"product_id":"9781475782622","title":"Apoptosis in Cardiac Biology","description":"\u003ch1\u003eApoptosis in Cardiac Biology\u003c\/h1\u003e \u003ch2\u003eSchunkert, Heribert; Riegger, G.A.J.\u003c\/h2\u003e \u003cp\u003eApoptosis or programmed cell death is increasingly considered  to be a major factor in the development and progression of  cardiovascular disease. In patients with heart failure the activation  of apoptosis may result in the loss of irreplaceable cardiac myocytes  promoting the clinical course of the syndrome. Moreover, in the  coronary arteries inflammation and apoptosis may weaken critical  structures of the vessel wall leading to plaque rupture and,  subsequently, to myocardial infarction. Given these deleterious  consequences, it seems almost paradoxical that programmed cell death  is an active process that, if initiated under physiological  circumstances, is essential for both coordinated tissue growth or  destruction of malignant cells. \u003cbr\u003e  \u003cem\u003eApoptosis in Cardiac Biology\u003c\/em\u003e, written by a team of  internationally renowned researchers, gives a timely synopsis of basic  mechanisms, cellular and structural targets and, finally, clinical  implications of programmed cell death in the heart. The expert authors  of this volume give concise overviews on general and cell-specific  aspects of programmed cell death in cardiac myocytes and fibroblasts,  as well as in vascular smooth muscle and endothelial cells.  Furthermore, novel therapeutic options arising from the outstanding  pathophysiological significance of cardiac apoptosis are presented.  \u003cbr\u003e  This comprehensive review of \u003cem\u003eApoptosis in Cardiac Biology\u003c\/em\u003e will  be of interest to both clinicians and basic researchers who are active  in the fields of cardiology and atherosclerosis.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2013-03-24\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003e ISBN-10: 9781475782622\u003c\/p\u003e \u003cp\u003eISBN-13: 9781475782622\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/b102337\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 354\u003c\/p\u003e ","brand":"Springer","offers":[{"title":"Default Title","offer_id":44358936035468,"sku":"9781475782622","price":198.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781475782622.jpg?v=1755098086","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781475782622","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}