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This book explores the many mechanisms by which the most prevalent Spirochetal pathogens persist in a healthy immune-competent host. Among them are the direct and indirect suppression of host immune signals, phase and antigenic variation, escaping recognition by host complement proteins, and seclusion into immune privileged sites. We also explore antibiotic therapy for control of infection, a baffling topic that lends itself to exalted interpretation.
Published by: Springer
Publication Date: 2012-12-07
Format: Hardcover
ISBN-13: 9781461454038
DOI: 10.1007/978-1-4614-5404-5
Dimensions: 235cm x155cm
Pages: 268