{"product_id":"9781461373469","title":"Environmental Metal Pollutants, Reactive Oxygen Intermediaries and Genotoxicity: Molecular Approaches to Determine Mechanisms of Toxicity","description":"\u003ch1\u003eEnvironmental Metal Pollutants, Reactive Oxygen Intermediaries and Genotoxicity: Molecular Approaches to Determine Mechanisms of Toxicity\u003c\/h1\u003e \u003ch2\u003eAriza, Maria E.; Bijur, Gautam N.; Williams, Marshall V.\u003c\/h2\u003e \u003cp\u003eHumans are exposed daily to low concentrations of metals that  are released into the environment by both natural and industrial  processes. \u003cem\u003eEnvironmental Metal Pollutants, Reactive Oxygen\u003c\/em\u003e  \u003cem\u003eIntermediaries and Genotoxicity: Molecular Approaches to  Determine\u003c\/em\u003e \u003cem\u003eMechanisms of Toxicity\u003c\/em\u003e examines concerns about the  acute and\/or chronic exposure of humans to concentrations of these  metals that are below the threshold levels established by various  federal regulatory agencies. Some of these metals are accumulated in  various tissues and over time this may result in the accumulation of a  significant body burden. This could increase the risk of developing a  variety of diseases later in life, at a time when thresholds for such  effects may already be reduced by the processes of aging. Such  possibilities could only further compromise the quality of life in the  elderly population and could contribute to the rising cost of health  care in this country. \u003cbr\u003e  Studies that have been conducted to determine the possible risks  associated with exposure to relatively non-toxic concentrations of  environmental metals have been hampered by a lack of appropriate  models and a lack of funding. It has also been difficult for  researchers to demonstrate a correlation between the exposure of  humans or animals to low concentrations of environmental pollutants  and disease. This book examines recent technological advances in the  areas of molecular biology, biochemistry, and computer-enhanced image  analyses that provide researchers with the tools to begin elucidating  the genotoxic effects of environmental metal pollutants and the  mechanisms by which these metals cause DNA damage. \u003cbr\u003e  \u003cem\u003eEnvironmental Metal Pollutants, Reactive Oxygen Intermediaries  and\u003c\/em\u003e \u003cem\u003eGenotoxicity: Molecular Approaches to Determine Mechanisms  of Toxicity\u003c\/em\u003e presents data that demonstrate that certain  environmental metal pollutants are genotoxic. The authors describe the  role of reactive oxygen intermediates in causing the DNA damage  induced by environmental metal pollutants and discuss their possible  role in human disease.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2012-10-09\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003e ISBN-10: 9781461373469\u003c\/p\u003e \u003cp\u003eISBN-13: 9781461373469\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-4615-5153-9\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 189\u003c\/p\u003e ","brand":"Springer","offers":[{"title":"Default Title","offer_id":44358754467980,"sku":"9781461373469","price":153.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781461373469.jpg?v=1755113393","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781461373469","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}