{"product_id":"9781461364405","title":"Emerging Targets in Antibacterial and Antifungal Chemotherapy","description":"\u003ch1\u003eEmerging Targets in Antibacterial and Antifungal Chemotherapy\u003c\/h1\u003e \u003ch2\u003eSutcliffe, Joyce; Georgopapadakou, Nafsika\u003c\/h2\u003e \u003cp\u003eEmerging Targets in Antibacterial and Antifungal Chemotherapy  offers constructive ideas to researchers that could lead to the  discovery of  entirely new classes of drugs. The authors emphasize new  topics  rather than review work on known antibacterials and  antifungals, and  identify new targets--either the rate-limiting  component of a  biochemical pathway or a component of the pathway that  is susceptible  to a ``screening'' or ``rational drug design''  approach. Each chapter  reviews the biochemical pathway and its place  in the cellular scheme  in order to place the target in perspective.  The authors, a mixture  of academic researchers and drug-discovery  investigators in  pharmaceutical companies, also extend these  theoretical concerns into  practical applications and suggest useful  screening methodologies.  The importance of this subject area is  demonstrated by the increasing  number of papers in the literature  that point to potential targets  and screening methodologies for new  antibacterials. This book also  deals with antifungals, investigating  the inherent limitations in  existing antifungals (many of which are  extremely toxic or have only  limited efficacy), and pointing to major  developments in the  discovery of novel antifungals. Emerging Targets  in Antibacterial and  Antifungal Chemotherapy will be of interest to  professional  microbiologists, biochemists, and cell biologists in  both academic  and industrial laboratories.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2012-10-21\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9781461364405\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-4615-3274-3\u003c\/p\u003e \u003cp\u003eDimensions: 235.0cm x155.0cm\u003c\/p\u003e \u003cp\u003ePages: 606.0\u003c\/p\u003e ","brand":"Springer US","offers":[{"title":"Default Title","offer_id":44408187617420,"sku":"9781461364405","price":197.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781461364405.jpg?v=1755787895","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781461364405","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}