{"product_id":"9781461356257","title":"Evolving Concepts in Sepsis and Septic Shock","description":"\u003ch1\u003eEvolving Concepts in Sepsis and Septic Shock\u003c\/h1\u003e \u003ch2\u003eEichacker, Peter Q.; Pugin, Jérôme\u003c\/h2\u003e \u003cp\u003eMuch research over the past 30 to 40 years has shown that the  inflammatory response, while critical for host defense during  microbial infection, may itself play a central role in the  pathogenesis of sepsis. Although key mediators responsible for this  injury have been identified, efforts clinically to augment our  conventional antimicrobial and supportive therapies during sepsis with  agents modulating the inflammatory response have been unsuccessful. As  a result, the mortality associated with this lethal syndrome,  especially when complicated by shock, has remained persistently high.  Unfortunately, during this same period of time, the incidence of  sepsis has accelerated as other fields of medicine have relied  increasingly on therapies that predispose to infection.\u003cbr\u003e  While frustrating, overall this experience in the field of sepsis has  not been without value. Most importantly, it has helped define on  several different levels the complexity of the septic patient.  Recognizing and addressing this complexity as discussed by each of the  contributors to \u003cem\u003eEvolving Concepts in Sepsis and Septic Shock\u003c\/em\u003e may  now provide new inroads into the treatment of sepsis.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2012-10-23\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003e ISBN-10: 9781461356257\u003c\/p\u003e \u003cp\u003eISBN-13: 9781461356257\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-4615-1581-4\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 195\u003c\/p\u003e ","brand":"Springer","offers":[{"title":"Default Title","offer_id":44343476519052,"sku":"9781461356257","price":153.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781461356257_b7d1e01d-ddb1-4b05-8bd0-da5bd972f0d9.jpg?v=1755056114","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781461356257","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}