{"product_id":"9781441961983","title":"Advances in Experimental Medicine and Biology","description":"\u003ch1\u003eAdvances in Experimental Medicine and Biology\u003c\/h1\u003e \u003ch2\u003ePoon, Randy Y.C.\u003c\/h2\u003e \u003cp\u003eLimiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation. A growing body of evidence indicates that the surveillance mechanisms that prevent polyploidization are frequently perturbed in cancers. Progress in the past several years has unraveled some of the underlying principles that maintain genome stability. This book brings together leaders of the field to overview\nsubjects relating to polyploidization and cancer.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2010-05-21\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9781441961983\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-4419-6199-0\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 151\u003c\/p\u003e ","brand":"Springer New York","offers":[{"title":"Default Title","offer_id":47976447705228,"sku":"9781441961983","price":152.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781441961983.jpg?v=1777374383","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781441961983","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}