{"product_id":"9781441948267","title":"Optimization in Computational Chemistry and Molecular Biology Local and Global Approaches","description":"\u003ch3\u003eNonconvex Optimization and Its Applications\u003c\/h3\u003e\u003ch1\u003eOptimization in Computational Chemistry and Molecular Biology\u003c\/h1\u003e\u003ch2\u003eLocal and Global Approaches\u003c\/h2\u003e\u003ch3\u003eChristodoulos A. Floudas | Panos M. Pardalos\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eComputers \/ Software Development \u0026amp; Engineering \/ General\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cem\u003eOptimization in Computational Chemistry and Molecular  Biology:\u003c\/em\u003e \u003cem\u003eLocal and Global Approaches\u003c\/em\u003e covers recent  developments in optimization techniques for addressing several  computational chemistry and biology problems. A tantalizing problem  that cuts across the fields of computational chemistry, biology,  medicine, engineering and applied mathematics is how proteins fold.  Global and local optimization provide a systematic framework of  conformational searches for the prediction of three-dimensional  protein structures that represent the global minimum free energy, as  well as low-energy biomolecular conformations. \u003cbr\u003e  Each contribution in the book is essentially expository in nature, but  of scholarly treatment. The topics covered include advances in local  and global optimization approaches for molecular dynamics and  modeling, distance geometry, protein folding, molecular structure  refinement, protein and drug design, and molecular and peptide  docking. \u003cbr\u003e  \u003cem\u003eAudience:\u003c\/em\u003e The book is addressed not only to researchers in  mathematical programming, but to all scientists in various disciplines  who use optimization methods in solving problems in computational  chemistry and biology.\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e06 December 2010\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eSpringer US\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eSpringer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9781441948267\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003ePaperback \/ softback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e342\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Springer US","offers":[{"title":"Default Title","offer_id":44358916243596,"sku":"9781441948267","price":152.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781441948267.jpg?v=1780592415","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781441948267","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}