Entrepreneurship in the Region approaches aspects of entrepreneurship from a regional perspective. Topics examined include peculiarities and disparities in new business formation processes, the success and the employment effects of new firms, the importance of social capital and of network structures as well as entrepreneurship education and training provided in the regions. The articles provide strong evidence for the importance of regional factors that shape entrepreneurship and new firm formation processes. The evidence clearly suggests that the regional level can be an appropriate starting point for entrepreneurship policy and that research on the issue may considerably benefit from properly accounting for the spatial dimension.