{"product_id":"9781405190916","title":"Catalysis in Asymmetric Synthesis","description":"\u003ch1\u003eCatalysis in Asymmetric Synthesis\u003c\/h1\u003e\u003ch3\u003eVittorio Caprio | Jonathan M. J. Williams\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eScience \/ Chemistry \/ Organic\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003e\u003cb\u003e\u003ci\u003eCatalysis in Asymmetric Synthesis,\u003c\/i\u003e 2nd Edition\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAsymmetric synthesis has become a major aspect of modern organic chemistry. The stereochemical properties of an organic compound are often essential to its bioactivity, and the need for stereochemically pure pharmaceutical products is a key example of the importance of stereochemical control in organic synthesis. However, achieving high levels of stereoselectivity in the synthesis of complex natural products represents a considerable intellectual and practical challenge for chemists.\u003c\/p\u003e \u003cp\u003eWritten from a synthetic organic chemistry perspective, this text provides a practical overview of the field, illustrating a wide range of transformations that can be achieved. The book captures the latest advances in asymmetric catalysis with emphasis placed on non-enzymatic methods.\u003c\/p\u003e \u003cp\u003eTopics covered include:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eReduction of alkenes, ketones and imines\u003c\/li\u003e \u003cli\u003eNucleophilic addition to carbonyl compounds\u003c\/li\u003e \u003cli\u003eCatalytic carbon-carbon bond forming reactions\u003c\/li\u003e \u003cli\u003eCatalytic reactions involving metal carbenoids\u003c\/li\u003e \u003cli\u003eConjugate addition reactions\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eCatalysis in Asymmetric Synthesis\u003c\/i\u003e bridges the gap between undergraduate and advanced level textbooks and provides a convenient point of entry to the primary literature for the experienced synthetic organic chemist.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e \u003cp\u003e\u003cb\u003eDr Vittorio Caprio,\u003c\/b\u003e Lecturer in Organic and Medicinal Chemistry in the Department of Chemistry, University of Auckland, New Zealand. His research interests lie in the application of synthetic organic methods to the synthesis of bioactive natural products of diverse structure. A central aim is the efficient and elegant syntheses of target core structures in a stereocontrolled manner using nature as the source of chirality. The ultimate goal is to use natural medicines as the basis for designing and synthesizing drugs of greater therapeutic value.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eProfessor Jonathan MJ Williams (author of the first edition),\u003c\/b\u003e Department of Chemistry, University of Bath, UK. Research involves with the use of transition metals for the synthesis of useful organic molecules. In particular, we have been developing reactions using 'borrowing hydrogen.' In this chemistry, ruthenium or iridium catalysts temporarily remove hydrogen to give an aldehyde.  This aldehyde then reacts to give an alkene (or imine) and the hydrogen is then returned to give a C-C or C-N bond. These procedures allow alcohols to be used as alkylating agents in place of more conventional, but often toxic\/mutagenic alkyl halides.\u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e16 March 2009\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley-Blackwell\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9781405190916\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e408\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e25.28\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44377673433228,"sku":"9781405190916","price":174.56,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781405190916.jpg?v=1780281454","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781405190916","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}