{"product_id":"9781405167208","title":"Fluorine in Medicinal Chemistry and Chemical Biology","description":"\u003ch1\u003eFluorine in Medicinal Chemistry and Chemical Biology\u003c\/h1\u003e\u003ch3\u003eIwao Ojima\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eScience \/ Chemistry \/ Industrial \u0026amp; Technical\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003eThe extraordinary potential of fluorine-containing molecules in medicinal chemistry and chemical biology has been recognized by researchers outside of the traditional fluorine chemistry field, and thus a new wave of fluorine chemistry is rapidly expanding its biomedical frontiers. With several of the best selling drugs in the world crucially containing fluorine atoms, the incorporation of fluorine to drug leads has become an essential practice in biomedical research, especially for drug design and discovery as well as development.  \u003cp\u003eFocusing on the unique and significant roles that fluorine plays in medicinal chemistry and chemical biology, this book reviews recent advances and future prospects in this rapidly developing field. Topics covered include:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eDiscovery and development of fluorine containing drugs and drug candidates.\u003c\/li\u003e \u003cli\u003eNew and efficient synthetic methods for medicinal chemistry and the optimisation of fluorine-containing drug candidates.\u003c\/li\u003e \u003cli\u003eStructural and chemical biology of fluorinated amino acids and peptides.\u003c\/li\u003e \u003cli\u003eFluorine labels as probes in metabolic study, protein engineering and clinical diagnosis.\u003c\/li\u003e \u003cli\u003eApplications of 19F NMR spectroscopy in biomedical research.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eAn appendix presents an invaluable index of all fluorine-containing drugs that have been approved by the US Food and Drug Administration, including information on structure and pharmaceutical action.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eFluorine in Medicinal Chemistry and Chemical Biology\u003c\/i\u003e will serve as an excellent reference source for graduate students as well as academic and industrial researchers who want to take advantage of fluorine in biomedical research.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e Professor Iwao Ojima is Distinguished Professor in the Department of Chemistry, and Director of the Institute of Chemical Biology \u0026amp; Drug Discovery, at the State University of New York at Stony Brook. He has published over 340 papers and reviews, more than 140 patents and patent applications, and edited 5 books, including \u003ci\u003eBiomedical Frontiers of Fluorine Chemistry\u003c\/i\u003e, published in the ACS Symposium Series in 1996. \u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e18 May 2009\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley-Blackwell\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9781405167208\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e656\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e43.2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44310667788428,"sku":"9781405167208","price":255.56,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781405167208.jpg?v=1781091896","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781405167208","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}