{"product_id":"9781402047947","title":"Computational studies of RNA and DNA","description":"\u003ch3\u003eChallenges and Advances in Computational Chemistry and Physics\u003c\/h3\u003e\u003ch1\u003eComputational studies of RNA and DNA\u003c\/h1\u003e\u003ch3\u003eJirí Šponer | Filip Lankaš\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eScience \/ Chemistry \/ Organic\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003e\u003cem\u003eComputational Studies of RNA and DNA\u003c\/em\u003e includes, in an integrated way, modern computational studies of nucleic acids, ranging from advanced electronic structure quantum chemical calculations through explicit solvent molecular dynamics (MD) simulations up to mesoscopic modelling, with the main focus given to the MD field. It gives an equal emphasis to the leading methods and applications while successes, as well as pitfalls of the computational techniques are discussed.\u003c\/p\u003e\r\n\u003cp\u003eThe systems and problems considered include:\u003c\/p\u003e\r\n\u003cp\u003e- Basic principles of nucleic acid structure and structural databases\u003cbr\u003e- Introduction to key molecular modelling tools and methods\u003cbr\u003e- Application of atomistic simulations to a wide variety of DNA and RNA systems \u003cbr\u003e- Accurate QM calculations of base pairing, stacking and cation binding\u003cbr\u003e- Charge transfer, excited states and NMR parameters\u003cbr\u003e- Calculating mechanical properties of nucleic acids\u003cbr\u003e- Mesoscopic simulation of DNA, chromatin modelling\u003c\/p\u003e\r\n\u003cp\u003eThis book is ideally suited to academics and researchers in organic and computational chemistry, structural molecular biology and biophysics as well as biochemistry, and particularly those interested in the molecular modelling of nucleic acids.\u003c\/p\u003e\r\n\u003cp\u003eBesides the state-of-the-art science, the book also provides extensive introductory information for non-specialists and students to enter and understand this field.\u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e20 September 2006\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eSpringer Netherlands\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eSpringer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9781402047947\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e638\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Springer Netherlands","offers":[{"title":"Default Title","offer_id":51556220731532,"sku":"9781402047947","price":197.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781402047947.jpg?v=1784771851","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781402047947","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}