{"product_id":"9781402044069","title":"Structure-based Drug Discovery","description":"\u003ch1\u003eStructure-based Drug Discovery\u003c\/h1\u003e \u003ch2\u003eJhoti, Harren; Leach, Andrew R.\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eStructure-based drug discovery methods have been transformed in the last 5-10 years and are now having a major impact on the discovery of new drugs. Some of the most exciting developments in the field, such as Fragment-based methods, are described in this book.\u003c\/p\u003e\n\u003cp\u003eThe book describes the latest developments in technologies that can be used to obtain the 3-D structures including the high profile structural genomics approaches being utilised worldwide. The use of 3-D protein structures in new, Fragment-based, approaches to drug discovery are described in some detail. This book includes experimental approaches using X-ray crystallography and NMR for Fragment-based screening as well as other biophysical methods for studying protein\/ligand interactions. In addition, developments in computational chemistry methodology are covered together with an assessment of practical applications.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2007-01-09\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9781402044069\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/1-4020-4407-0\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 250\u003c\/p\u003e ","brand":"Springer Netherlands","offers":[{"title":"Default Title","offer_id":49471494291596,"sku":"9781402044069","price":98.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781402044069.jpg?v=1777985331","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781402044069","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}