{"product_id":"9781394300129","title":"Drug Metabolism and Pharmacokinetics Frontiers, Strategies, and Applications","description":"\u003ch1\u003eDrug Metabolism and Pharmacokinetics\u003c\/h1\u003e\u003ch2\u003eFrontiers, Strategies, and Applications\u003c\/h2\u003e\u003ch3\u003eLiang Shen | WuXi AppTec DMPK\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eMedical \/ Pharmacology\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003e\u003cb\u003ePractical, state-of-the-art pharmacokinetic research methods, ideas, advancements, applications, and strategies\u003c\/b\u003e \u003c\/p\u003e\n\u003cp\u003eDrawing on a wealth of extensive practical experience and theoretical research, \u003ci\u003eDrug Metabolism and Pharmacokinetics\u003c\/i\u003e encapsulates the most recent advancements and illustrative applications in the field. Sixty-eight relatively independent yet interconnected articles are included, each offering a unique perspective and providing in-depth interpretation. Readers can either read systematically or select specific topics of interest from the table of contents. \u003c\/p\u003e\n\u003cp\u003eBasic concepts, frontier advancements, DMPK research strategies, and technical methods are covered for novel drug modalities and therapeutics in different disease areas. The book encompasses a wide range of application and validation cases for DMPK research, including studies in \u003ci\u003ein vitro \u003c\/i\u003eADME, \u003ci\u003ein vivo \u003c\/i\u003epharmacokinetics, metabolite profiling and identification, radiolabeled ADME, and bioanalysis. Case studies showing the application of topics covered are included throughout, along with valuable insights into problem-solving and critical thinking. \u003c\/p\u003e\n\u003cp\u003eWritten by a team of scientists specializing in DMPK research from the DMPK Department of WuXi AppTec, \u003ci\u003eDrug Metabolism and Pharmacokinetics\u003c\/i\u003e discusses sample topics including: \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eADME properties, metabolite identification, and bioanalytical strategies for oligonucleotide drugs\u003c\/li\u003e\n\u003cli\u003eStrategies and challenges in the determination of drug-to-antibody ratio (DAR) values of antibody-drug conjugates (ADCs)\u003c\/li\u003e\n\u003cli\u003eBreaking barriers in CNS drug development with intrathecal and intracerebroventricular administration\u003c\/li\u003e\n\u003cli\u003eApplication and detection techniques of biomarkers in drug development\u003c\/li\u003e\n\u003cli\u003eFlux dialysis method for assessing plasma protein binding of high protein-binding drugs\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003e\u003ci\u003eDrug Metabolism and Pharmacokinetics\u003c\/i\u003e is an essential forward-thinking reference on the subject for pharmacy students, pharmaceutical industry researchers, and DMPK scientists, especially those exploring novel drug modalities.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e  \u003cp\u003e\u003cb\u003eLiang Shen, PhD,\u003c\/b\u003e is the head of DMPK at WuXi AppTec. \u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e09 July 2025\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9781394300129\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e576\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e45.6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44380810379404,"sku":"9781394300129","price":264.56,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781394300129_04cbaf02-6635-483c-9411-c9d33f51ec53.jpg?v=1780108497","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781394300129","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}