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Techno-Economic Modeling for Chemical and Bioprocess Innovations

Techno-Economic Modeling for Chemical and Bioprocess Innovations

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Techno-Economic Modeling for Chemical and Bioprocess Innovations

Chris Burk

Technology & Engineering / Chemical & Biochemical

Build spreadsheet-based techno-economic models to understand factors driving economic value

Techno-economic modeling examines how technical and financial parameters influence the economic value of a technology at the commercial scale. Techno-Economic Modeling for Chemical and Bioprocess Innovations is a practical guide to building spreadsheet-based techno-economic models and using them to make better decisions on the road to market.

Inside, this book:

  • Explains the role of techno-economic modeling in advancing new technologies toward commercialization.
  • Presents spreadsheet best practices that form the foundation for effective and efficient techno-economic modeling.
  • Teaches how to combine process modeling, equipment sizing, and cost estimation in a cohesive and usable spreadsheet model.
  • Introduces techniques for analyzing model results to assess economic viability, quantify uncertainty, inform R&D priorities, and improve stakeholder communication.
  • Provides practical Excel and VBA examples, with two complete sample models available online.

This book equips readers with the tools to combine science, engineering, and cost estimation. It is an essential resource for chemical and bioprocess engineers, including academics, startup teams, and advanced students working to bring innovations into the world.

Chris Burk is a chemical engineer and consultant. He is a leader in the field of techno-economic modeling for tough-tech innovations. Chris has developed models for over 100 technologies, built a library of software tools, and has written and spoken extensively on the subject. He regularly works with startups from the top tough-tech focused organizations in the United States, such as Activate and MIT’s The Engine, as well as many others.


Publication Date: 28 October 2025
Publisher: Wiley
Imprint: Wiley
ISBN-13: 9781394246410
Format: Paperback / softback
Page Count: 368
Weight (oz): 20.8

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