{"product_id":"9781119976097","title":"Toxicology and Epigenetics","description":"\u003ch1\u003eToxicology and Epigenetics\u003c\/h1\u003e\u003ch3\u003eSaura C. Sahu\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eScience \/ Chemistry \/ Industrial \u0026amp; Technical\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003eEpigenetics is the study of both heritable and non-heritable changes in the regulation of gene activity and expression that occur without an alteration in the DNA sequence\u003cb\u003e.\u003c\/b\u003e This dynamic and rapidly developing discipline is making its impact across the biomedical sciences, in particular in toxicology where epigenetic differences can mean that different individuals respond differently to the same drug or chemical.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eToxicology and Epigenetics\u003c\/i\u003e reflects the multidimensional character of this emerging area of toxicology, describing cutting-edge molecular technologies to unravel epigenetic changes, the use of \u003ci\u003ein vivo\u003c\/i\u003e and \u003ci\u003ein vitro\u003c\/i\u003e models, as well as the potential use of toxicological epigenetics in regulatory environments. An international team of experts consider the interplay between epigenetics and toxicology in a number of areas, including environmental, nutritional, pharmacological, and computational toxicology, nanomaterials, proteomics and metabolomics, and cancer research.\u003c\/p\u003e \u003cp\u003eTopics covered include:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eenvironment, epigenetics and diseases\u003c\/li\u003e \u003cli\u003eDNA methylation and toxicogenomics\u003c\/li\u003e \u003cli\u003echromatin at the intersection of disease and therapy\u003c\/li\u003e \u003cli\u003eepigenomic actions of environmental arsenicals\u003c\/li\u003e \u003cli\u003eenvironment, epigenetics and cardiovascular health\u003c\/li\u003e \u003cli\u003etoxicology, epigenetics and autoimmunity\u003c\/li\u003e \u003cli\u003eocular epigenomics: potential sites of environmental impact in development and disease\u003c\/li\u003e \u003cli\u003enuclear RNA silencing and related phenomena in animals\u003c\/li\u003e \u003cli\u003eepigenomics – impact for drug safety sciences\u003c\/li\u003e \u003cli\u003emethods of global epigenomic profiling\u003c\/li\u003e \u003cli\u003etranscriptomics: applications in epigenetic toxicology\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eToxicology and Epigenetics\u003c\/i\u003e is an essential insight into the current trends and future directions of research in this rapidly expanding field for investigators, toxicologists, risk assessors and regulators in academia, industry and government.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e  \u003cp\u003e\u003cstrong\u003eDr. Saura C. Sahu\u003c\/strong\u003e, Research Chemist, Division of Toxicology, Office of Applied Research and Safety Assessment, Center for Food Safety and Applied Nutrition, US Food and Drug Administration.\u003cbr\u003eDr. Sahu is the US Editor for the \u003cem\u003eJournal of Applied Toxicology\u003c\/em\u003e and the editor of \u003cem\u003eHepatotoxicity\u003c\/em\u003e (Wiley, 2007), \u003cem\u003eToxicogenomics\u003c\/em\u003e (Wiley, 2008), \u003cem\u003eNanotoxicity\u003c\/em\u003e (Wiley, 2009), and \u003cem\u003eHandbook of Systems Toxicology\u003c\/em\u003e (Wiley, 2011). \u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e08 October 2012\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9781119976097\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e688\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e45.76\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44384612974732,"sku":"9781119976097","price":270.86,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781119976097_ac802bf1-5610-49d7-a713-60d6c45e6252.jpg?v=1780181991","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781119976097","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}