{"product_id":"9781118057452","title":"Absorption and Drug Development Solubility, Permeability, and Charge State","description":"\u003ch1\u003eAbsorption and Drug Development\u003c\/h1\u003e\u003ch2\u003eSolubility, Permeability, and Charge State\u003c\/h2\u003e\u003ch3\u003eAlex Avdeef\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eMedical \/ Pharmacology\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003e\u003cb\u003eExplains how to perform and analyze the results of the latest physicochemical methods\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eWith this book as their guide, readers have access to all the current information needed to thoroughly investigate and accurately determine a compound's pharmaceutical properties and their effects on drug absorption. The book emphasizes oral absorption, explaining all the physicochemical methods used today to analyze drug candidates. Moreover, the author provides expert guidance to help readers analyze the results of their studies in order to select the most promising drug candidates.\u003c\/p\u003e \u003cp\u003eThis \u003ci\u003eSecond Edition\u003c\/i\u003e has been thoroughly updated and revised, incorporating all the latest research findings, methods, and resources, including:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eDescriptions and applications of new PAMPA models, drawing on more than thirty papers published by the author's research group\u003c\/li\u003e \u003cli\u003eTwo new chapters examining permeability and Caco-2\/MDCK and permeability and the blood-brain barrier\u003c\/li\u003e \u003cli\u003eExpanded information and methods to support pKa determination\u003c\/li\u003e \u003cli\u003eNew examples explaining the treatment of practically insoluble test compounds\u003c\/li\u003e \u003cli\u003eAdditional case studies demonstrating the use of the latest physicochemical techniques\u003c\/li\u003e \u003cli\u003eNew, revised, and expanded database tables throughout the book\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eWell over 200 drawings help readers better understand difficult concepts and provide a visual guide to complex procedures. In addition, over 800 references serve as a gateway to the primary literature in the field, facilitating further research into all the topics covered in the book.\u003c\/p\u003e \u003cp\u003eThis \u003ci\u003eSecond Edition\u003c\/i\u003e is recommended as a reference for researchers in pharmaceutical R\u0026amp;D as well as in agrochemical, environmental, and other related areas of research. It is also recommended as a supplemental text for graduate courses in pharmaceutics.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e \u003cp\u003e\u003cb\u003eALEX AVDEEF\u003c\/b\u003e, PhD, is the founder of in-ADME Research. He has more than thirty years of experience in chemical instrumentation and software development. Internationally recognized as an authority in the field of solution chemistry, Dr. Avdeef has an extensive list of scholarly publications to his credit.\u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e22 May 2012\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9781118057452\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e744\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e40.0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44380467265676,"sku":"9781118057452","price":170.96,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781118057452.jpg?v=1780142015","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781118057452","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}