Methods in Molecular Biology

Peng, Huan; Lim, Theam Soon

This volume explores major biomolecular display platforms and their applications, which allow researchers to mine vast, diverse libraries for functional variants, bridging molecular design and real-world application. Beginning with a section on foundational techniques for functional libraries, the book continues by covering tailored yeast, phage, and cDNA display strategies to boost efficiency, modulate binding, and engineer scaffolds for specialized needs, display-driven identification of macrocyclic ligands, nanoparticle-binding peptides, epitopes, and functional proteins, as well as computational advances, protein engineering, and post-selection analysis to refine hits and accelerate translation. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.

Authoritative and practical, Biomolecular Display Technologies offers expert guidance and insight into the transformative potential of display technologies.

Details

Published by: Humana

Publication Date: 2026-07-03

Format: Hardcover

ISBN-13: 9781071652480

DOI:

Dimensions: 254cm x178cm

Pages: 325