{"product_id":"9781071648278","title":"Methods in Molecular Biology: Methods and Protocols","description":"\u003ch1\u003eMethods in Molecular Biology: Methods and Protocols\u003c\/h1\u003e \u003ch2\u003eKhan, Shahid M.; Pazos, Florencio\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan style=\"font-family: 'Times New Roman',serif;\"\u003eThis volume details computational tools for the study of protein evolution based on 1D-sequence and 3D-structure databases. Chapters guide readers through the analysis of 1D protein sequences for coevolutionary fold prediction, protein-nucleic acid interactions, distant homologs and functional motifs, characterization of fold energetics, disordered proteins, mutagenesis-driven modulation of conformational landscapes, 3D protein domains, prediction of 3D protein-protein interactions, and hybrid methods that mine both 1D and 3D genomic and protein databases for gene editing and alternative splicing. Written in the highly successful \u003cem\u003eMethods in Molecular Biology \u003c\/em\u003eseries format, the chapters include brief introductions to\u003cem\u003e \u003c\/em\u003ethe material, lists of necessary materials and reagents, step-by-step, readily\u003cem\u003e \u003c\/em\u003ereproducible laboratory protocols, and a Notes section which highlights\u003cem\u003e \u003c\/em\u003etips on troubleshooting and avoiding known pitfalls.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan style=\"font-family: 'Times New Roman',serif;\"\u003eAuthoritative and cutting-edge, \u003cem\u003eProtein Evolution: Methods and Protocols \u003c\/em\u003eaims to be comprehensive guide for\u003cem\u003e \u003c\/em\u003eresearchers in the field.\u003c\/span\u003e\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2025-11-02\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9781071648278\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-0716-4828-5\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 320\u003c\/p\u003e ","brand":"Springer US","offers":[{"title":"Default Title","offer_id":44309254701196,"sku":"9781071648278","price":197.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781071648278.jpg?v=1772892449","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781071648278","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}