Methods in Molecular Biology

Verma, Paul John; Sumer, Huseyin; Liu, Jun

This volume details generation of gene-edited cell lines and organisms as models for human diseases, pest control, and large animal welfare and production outcomes. Chapters guide readers through gene regulation, editing, screening of cell lines, genome editing, and an overview of the tools for efficient genome editing including; ZFNs, TALENs, and CRISPR. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step- by-step, readily reproducible protocols.

Authoritative and cutting-edge, Applications of Genome Modulation and Editing aims to be a useful and practical guide for researchers to commence or advance their study in this field.

Details

Published by: Humana

Publication Date: 2022-06-14

Format: Hardcover

ISBN-13: 9781071623008

DOI: 10.1007/978-1-0716-2301-5

Dimensions: 254cm x178cm

Pages: 369