{"product_id":"9781071616642","title":"Targeted Protein Degradation: Methods and Protocols","description":"\u003ch1\u003eTargeted Protein Degradation: Methods and Protocols\u003c\/h1\u003e \u003ch2\u003eCacace, Angela M.; Hickey, Christopher M.; Békés, Miklós\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis volume contains a collection of innovative techniques for studying targeted protein degradation. Chapters guide readers through heterobifunctional proteolysis-targeting chimeras (PROTACs) approaches, E3 ligase, E3 ligase-induced ubiquitylation, proteomic approaches, novel degrader molecules, molecular glue, and stabilize binding interaction between a target and E3 ubiquitin ligase. Written in the format of the highly successful \u003ci\u003eMethods in Molecular Biology \u003c\/i\u003eseries, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.\u003c\/p\u003e\n\n\u003cp\u003e \u003c\/p\u003e\n\n\u003cp\u003eAuthoritative and cutting-edge, \u003ci\u003eTargeted Protein Degradation: Methods and Protocols\u003c\/i\u003e aims to ensure successful results in this emerging field of drug discovery.\u003c\/p\u003e\n\n\u003cp\u003e \u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2021-08-26\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9781071616642\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-0716-1665-9\u003c\/p\u003e \u003cp\u003eDimensions: 254.0cm x178.0cm\u003c\/p\u003e \u003cp\u003ePages: 351.0\u003c\/p\u003e ","brand":"Springer US","offers":[{"title":"Default Title","offer_id":44806633750668,"sku":"9781071616642","price":224.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781071616642.jpg?v=1763577027","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781071616642","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}