{"product_id":"9781071602812","title":"Methods in Molecular Biology","description":"\u003ch1\u003eMethods in Molecular Biology\u003c\/h1\u003e \u003ch2\u003eHeifetz, Alexander\u003c\/h2\u003e \u003cp\u003eThis volume looks at applications of quantum mechanical (QM) methods in drug discovery. The chapters in this book describe how QM approaches can be applied to address key drug discovery issues, such as characterizing protein-water-ligand and protein-protein interactions, providing estimates of binding affinities, determining ligand energies and bioactive conformations, refinement of molecular geometries, scoring docked protein–ligand poses, describing molecular similarity, structure–activity-relationship (SAR) analysis, and ADMET prediction. Written in the highly successful \u003cem\u003eMethods in Molecular Biology \u003c\/em\u003eseries format, chapters include introductions to their respective topics, lists of the necessary software and tools, step-by-step, readily reproducible modeling protocols, and tips on troubleshooting and avoiding known pitfalls. \u003c\/p\u003e\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\u003cdiv\u003eCutting-edge and unique, \u003ci\u003eQuantum Mechanics in Drug Discovery\u003c\/i\u003e\u003cb\u003e \u003c\/b\u003eis a valuable resourcefor structural and molecular biologists, computational and medicinal chemists, pharmacologists, and drug designers.\u003c\/div\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2020-02-04\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9781071602812\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-0716-0282-9\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 360\u003c\/p\u003e ","brand":"Springer US","offers":[{"title":"Default Title","offer_id":46543111717004,"sku":"9781071602812","price":224.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781071602812.jpg?v=1772848478","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781071602812","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}