{"product_id":"9780813815350","title":"Biomarkers for Antioxidant Defense and Oxidative Damage Principles and Practical Applications","description":"\u003ch1\u003eBiomarkers for Antioxidant Defense and Oxidative Damage\u003c\/h1\u003e\u003ch2\u003ePrinciples and Practical Applications\u003c\/h2\u003e\u003ch3\u003eGiancarlo Aldini | Kyung-Jin Yeum | Etsuo Niki | Robert M. Russell\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eMedical \/ Nutrition\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003ci\u003eBiomarkers for Antioxidant Defense and Oxidative Damage: Principles and Practical Applications\u003c\/i\u003e critically evaluates the basic concepts and methodologies of conventional biomarkers as well as current state-of-the-art assays for measuring antioxidant activity\/oxidative stress and their practical applications. . \u003ci\u003eBiomarkers for Antioxidant Defense and Oxidative Damage: Principles and Practical Applications\u003c\/i\u003e will be of a great interest to scientists who are involved in basic research on oxidation, applied scientists evaluating the effects of nutraceuticals or pharmaceutical compounds on antioxidant activity\/oxidative stress, and physicians who want to understand the degree of oxidative damage in patients with certain chronic diseases.  \u003cp\u003eDiscovering sensitive and specific biomarkers for systemic oxidative damage is essential to understand the role of oxidative stress in human disease. Once these roles are clearly understood, we are able to identify novel drug and nutraceutical targets. This volume goes beyond conventional analytical methods of measuring overall antioxidant activity and provides insight to the discovery of biomarkers that reveal information on specific areas of oxidative stress. Contributed by an international list of experts, \u003ci\u003eBiomarkers for Antioxidant Defense and Oxidative Damage: Principles and Practical Applications\u003c\/i\u003e describes both conventional biomarkers and recent developments in this area.\u003c\/p\u003e \u003cp\u003eSpecial Features:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eDiscusses conventional biomarkers as well as recent advances for measuring antioxidants and oxidative stress\u003c\/li\u003e \u003cli\u003eBiomarkers for lipid peroxidation: isoprostane, hydroxyloctadecaenoic acid, oxysterols, and reactive carbonyl species from lipid peroxidation\u003c\/li\u003e \u003cli\u003eBiomarkers for protein oxidation: carbonylation, tyrosine oxidation, ubiquitin-conjugation\u003c\/li\u003e \u003cli\u003eBiomarkers for DNA oxidative damage: comet assay, hydroxylated nucleotides, and exocylcic DNA adducts\u003c\/li\u003e \u003cli\u003eRecently developed biomarkers from cutting-edge technology\u003c\/li\u003e \u003c\/ul\u003e\n\u003c\/div\u003e\u003cdiv\u003e  \u003cb\u003eGiancarlo Aldini\u003c\/b\u003e, Ph.D., Department of Pharmaceutical  \u003cp\u003eSciences \"Pietro Pratesi\", Università degli Studi di Milano, Milan, Italy\u003c\/p\u003e \u003cp\u003e\u003cb\u003eKyung-Jin Yeum\u003c\/b\u003e, Ph.D., Jean Mayer USDA-Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eEtsuo Niki\u003c\/b\u003e, Ph.D., , Health Research Institute, National Institute of Advanced Industrial Science \u0026amp; Technology, Osaka, Japan.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eRobert M. Russell\u003c\/b\u003e, M.D., Office of Dietary Supplements, National Institutes of Health, 6100 Executive Blvd., Bethesda, MD 20892-7517, USA\u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e05 October 2010\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley-Blackwell\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9780813815350\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e380\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e32.0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44379065450636,"sku":"9780813815350","price":262.76,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780813815350_296c8061-f139-4028-9b06-9b2a9ffaf599.jpg?v=1780103414","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9780813815350","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}