{"product_id":"9780792380085","title":"Developments in Cardiovascular Medicine","description":"\u003ch1\u003eDevelopments in Cardiovascular Medicine\u003c\/h1\u003e \u003ch2\u003eLafont, Antoine; Topol, Eric J.\u003c\/h2\u003e \u003cp\u003eAngioplasty has completely transformed the treatment of  coronary artery disease and is widely used, with more than 800,000  procedures performed  worldwide per year. However, the enthusiasm for  angioplasty is shadowed  by restenosis, which remains a critical  problem after the procedure,  resulting in clinical recurrence in over  a third of patients. Recently, the mechanisms of restenosis have been  completely reappraised with an  enriched understanding that the  original concept of neointimal hyperplasia  may not be accounting for  the bulk of the problem. \u003cbr\u003e There is a desperate need to heighten  understanding of the remodeling  process at the molecular, cellular,  and arterial level. Vascular remodeling is a well established concept  in the field of atherosclerosis and hypertension,  but only in recent  years has its applicability to the field of restenosis  become  pivotal. Accordingly, the editors perceived the need to assemble the  first book dedicated to the concept of coronary artery remodeling in  restenosis, in order to clearly review the experiments leading to the  remodeling hypothesis and integrate this with the neointimal  hyperplasia  (tumor) model for the development of the restenotic  lesion. \u003cbr\u003e The authors of this book present their experience to  facilitate the  understanding of the mechanisms for coronary  restenosis and remodeling.  The various experimental models, clinical  issues, and basic mechanisms are  reviewed in detail, resulting in a  fresh approach to a vexing clinical  problem. \u003cem\u003eArterial Remodeling:  A Critical Factor in Restenosis\u003c\/em\u003e will  be useful to the physician  and trainee who have an interest in restenosis,  and specifically in  the major pathophysiologic process which determines  the fate of  arterial healing in patients following percutaneous coronary  revascularization. It is hoped that this book will lay the foundation  for more effective therapies that will reduce the chance of  constrictive remodeling  and improve the long-term efficacy of  non-surgical coronary revascularization in the future.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 1997-10-31\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9780792380085\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-4615-6079-1\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 569\u003c\/p\u003e ","brand":"Springer US","offers":[{"title":"Default Title","offer_id":46311862304908,"sku":"9780792380085","price":197.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780792380085.jpg?v=1771513499","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9780792380085","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}