{"product_id":"9780792328971","title":"Developments in Cardiovascular Medicine","description":"\u003ch1\u003eDevelopments in Cardiovascular Medicine\u003c\/h1\u003e \u003ch2\u003eArdissino, Gianluigi; Opie, Lionel H.; Savonitto, Stefano\u003c\/h2\u003e \u003cp\u003eAlthough there are many books on angina, few are devoted to the  important problem of how to evaluate drug efficacy in angina pectoris.  \u003cem\u003eDrug Evaluation in Angina Pectoris\u003c\/em\u003e has two fundamental aims: the  first is to review the methodological aspects of drug evaluation in  stable and unstable angina pectoris; the second is to provide a  logical and methodological background for future studies aimed at  assessing the ability of medical treatment to improve prognosis. \u003cbr\u003e  Part I updates the pathophysiology, clinical presentation and  prognosis of angina pectoris. Part II aims to `put in numbers' the  symptoms and signs of myocardial ischemia, starting from a revision of  the currently used parameters. It is extremely important to quantify  the variability of the disease for the correct design of clinical  trial, a subject dealt with in Part III, which also discusses some  clinico-pharmacological aspects of therapy. Part IV is a critical  review of the drugs currently used for the treatment of stable and  unstable angina, and particularly considers some important unresolved  issues concerning their use. The current FDA and EC guidelines for the  evaluation of antianginal drugs are briefly discussed in Part V,  giving clinical investigators insight into how antianginal drugs are  evaluated by regulatory agencies and what is considered as proof of a  valid efficacy\/tolerability ratio. \u003cbr\u003e  \u003cem\u003eDrug Evaluation in Angina Pectoris\u003c\/em\u003e will assist discerning  cardiologists, pharmacologists, and advanced students of cardiology as  well as innovative pharmaceutical companies, all of whom need to  understand what angina is, how to evaluate treatment, and how to judge  the agents used in its treatment. \u003cbr\u003e\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 1994-11-30\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9780792328971\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-4615-2628-5\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 262\u003c\/p\u003e ","brand":"Springer US","offers":[{"title":"Default Title","offer_id":46311860404364,"sku":"9780792328971","price":152.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780792328971.jpg?v=1771513476","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9780792328971","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}