Presents a coherent view of autoreactivity in health and disease and considers potential new approaches to the therapy of autoimmune diseases. This volume is a vital source of information for clinicians, researchers, faculty, and students in microbiology, immunology and pathology.

António Manuel Pinto Amaral Coutinho is a Portuguese immunologist, and as of 2010 the only Portuguese ISI highly cited researcher. He has been Director of the Instituto Gulbenkian de Ciência since 1998. Michel Kazatchkine is a French physician, diplomat and advocate, best known for his work in international AIDS treatment issues. From February 2007 to March 2012 he was director of The Global Fund to Fight AIDS, Tuberculosis and Malaria.