Provides an account of the preparation, properties, and uses of the more important bi- and tri-cyclic ring systems incorporating the pyrazine ring. The first 18 chapters survey the developments in the chemistry of quinoxalines since the appearance in 1953 of a previous monograph in this series. The subsequent 22 chapters provide the first authoritative reviews of the chemistry of such important related ring systems as the pyrrolopyrazines.

G. W. H. Chesseman, Department of Chemistry, Queen Elizabeth College, University of London, UK.

R. F. Cookson, Janssen Pharmaceutical Ltd.