{"product_id":"9780470927946","title":"Pharmacogenomics of Human Drug Transporters Clinical Impacts","description":"\u003ch1\u003ePharmacogenomics of Human Drug Transporters\u003c\/h1\u003e\u003ch2\u003eClinical Impacts\u003c\/h2\u003e\u003ch3\u003eToshihisa Ishikawa | Richard B. Kim | Jörg König\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eMedical \/ Pharmacology\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003e\u003cb\u003eSets the foundation for safer, more effective drug therapies\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eWith this book as their guide, readers will discover how to apply our current understanding of the pharmacogenomics of drug transporters to advance their own drug discovery and development efforts. In particular, the book explains how new findings in the field now enable researchers to more accurately predict drug interactions and adverse drug reactions. Moreover, it sets the foundation for the development of drug therapies that are tailored to an individual patient's genetics.\u003c\/p\u003e \u003cp\u003e\u003ci\u003ePharmacogenomics of Human Drug Transporters\u003c\/i\u003e serves as a comprehensive guide to how transporters regulate the absorption, distribution, and elimination of drugs in the body as well as how an individual's genome affects those processes. The book's eighteen chapters have been authored by a team of leading pioneers in the field. Based on their own laboratory and clinical experience as well as a thorough review of the literature, these authors explore all facets of drug transporter pharmacogenomics, including:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eIndividual drug transporters and transporter families and their clinical significance\u003c\/li\u003e \u003cli\u003ePrinciples of altered drug transport in drug–drug interactions, pharmacotherapy, and personalized medicine\u003c\/li\u003e \u003cli\u003eEmerging new technologies for rapid detection of genetic polymorphisms\u003c\/li\u003e \u003cli\u003eClinical aspects of genetic polymorphisms in major drug transporter genes\u003c\/li\u003e \u003cli\u003eFuture research directions of drug transporter pharmacogenomics and the prospect of individualized medicine\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003ePharmacogenomics of Human Drug Transporters\u003c\/i\u003e opens the door to new drug discovery and development breakthroughs leading to safer and more effective customized drug therapies.The book is recommended for pharmaceutical scientists, biochemists, pharmacologists, clinicians, and genetics and genomics researchers.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e  \u003cp\u003e\u003cb\u003eTOSHIHISA ISHIKAWA, PhD,\u003c\/b\u003e is Senior Scientist at RIKEN Yokohama Institute and Professor of Biochemistry, Molecular Biology, and Pharmacogenomics at Yokohama City University's Graduate School of Medicine. Previously, Dr. Ishikawa was the Director of the Department of Research Technology Development at Pfizer, Japan. A recipient of the Achievement Award from the International Life Sciences Institute (ILSI), Dr. Ishikawa is also the cofounder of the International Transporter Consortium (ITC).\u003c\/p\u003e \u003cp\u003e\u003cb\u003eRICHARD B. KIM, MD, FRCPC,\u003c\/b\u003e is Professor and Chair of the Division of Clinical Pharmacology and Associate Chair for Research in the Department of Medicine at the University of Western Ontario. He is a Fellow of the American Association of Pharmaceutical Scientists and an elected member of the American Society for Clinical Investigation.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eJÖRG KÖNIG\u003c\/b\u003e, \u003cb\u003ePhD,\u003c\/b\u003e is Professor and Head of the Molecular Biology Laboratories in the Department of Clinical Pharmacology at the Friedrich-Alexander Universität Erlangen-Nürnberg.\u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e15 April 2013\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9780470927946\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e434\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e26.4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44310891593868,"sku":"9780470927946","price":166.46,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780470927946_0bc4b161-ab72-4c58-81e5-9176884fb92f.jpg?v=1780204969","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9780470927946","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}