{"product_id":"9780470874325","title":"Cholesterol Regulation of Ion Channels and Receptors","description":"\u003ch1\u003eCholesterol Regulation of Ion Channels and Receptors\u003c\/h1\u003e\u003ch3\u003eIrena Levitan | Francisco Barrantes\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eScience \/ Life Sciences \/ Molecular Biology\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003e\u003cb\u003eExamines new research on the role of cholesterol in regulating ion channels and receptors and its effect on health\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eDrawing together and analyzing all the latest research findings, this book explores the role of cholesterol in the regulation of ion channels and receptors, including its pathological effects. It is the first book to comprehensively describe the complex mechanisms by which cholesterol regulates two major classes of membrane proteins. Moreover, it sheds new light on how cholesterol affects essential cellular functions such as the contraction of the heart, propagation of nerve impulses, and regulation of blood pressure and kidney function.\u003c\/p\u003e \u003cp\u003eWritten and edited by leading pioneers in the field, \u003ci\u003eCholesterol Regulation of Ion Channels and Receptors\u003c\/i\u003e is divided into three parts:\u003c\/p\u003e \u003cul\u003e \u003cli\u003ePart I, \u003ci\u003eCholesterol Regulation of Membrane Properties\u003c\/i\u003e, introduces the heterogeneity of cholesterol distribution in biological membranes and the physical and biological implications of the formation of cholesterol-rich membrane domains.\u003c\/li\u003e \u003cli\u003ePart II, \u003ci\u003eCholesterol Regulation of Ion Channels\u003c\/i\u003e, examines the mechanisms underlying cholesterol sensitivities of ion channels, including the regulation of ion channels by cholesterol as a boundary lipid.\u003c\/li\u003e \u003cli\u003ePart III, \u003ci\u003eCholesterol Regulation of Receptors\u003c\/i\u003e, explores the latest discoveries concerning how cholesterol regulates distinct types of receptors, including G-protein coupled receptors, LDL and scavenger receptors, and innate immune system receptors.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eIncreased levels of cholesterol represent a major health risk. Understanding cholesterol regulation of ion channels and receptors is essential for facilitating the development of new therapeutic strategies to alleviate the impact of pathological cholesterol conditions. With this book as their guide, readers have access to the most current knowledge in the field.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e  \u003cp\u003e\u003cb\u003eIRENA LEVITAN, PhD\u003c\/b\u003e, is Associate Professor of Medicine at the University of Illinois College of Medicine at Chicago. Her research interests focus on the impact of dyslipidemia on K+ channels and endothelial biomechanics.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eFRANCISCO J. BARRANTES\u003c\/b\u003e is the former head of the National Research Council (CONICET) – Bahia Blanca and UNESCO Chair of Biophysics and Molecular Neurobiology. Currently, he is Director of the Laboratory of Molecular Neurobiology and Professor at the Faculty of Medical Sciences, Pontifical Catholic University of Argentina. His current research interests focus on the understanding of nicotinic acetylcholine receptor-membrane cross-talk.\u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e31 July 2012\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9780470874325\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e302\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e20.0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44311128539276,"sku":"9780470874325","price":143.06,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780470874325.jpg?v=1780233553","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9780470874325","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}