{"product_id":"9780470624227","title":"Protein Families Relating Protein Sequence, Structure, and Function","description":"\u003ch3\u003eWiley Series in Protein and Peptide Science\u003c\/h3\u003e\u003ch1\u003eProtein Families\u003c\/h1\u003e\u003ch2\u003eRelating Protein Sequence, Structure, and Function\u003c\/h2\u003e\u003ch3\u003eChristine A. Orengo | Alex Bateman | Vladimir Uversky\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eScience \/ Bioinformatics\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003eNew insights into the evolution and nature of proteins\u003c\/p\u003e \u003cp\u003eExploring several distinct approaches, this book describes the methods for comparing protein sequences and protein structures in order to identify homologous relationships and classify proteins and protein domains into evolutionary families. Readers will discover the common features as well as the key philosophical differences underlying the major protein classification systems, including Pfam, Panther, SCOP, and CATH. Moreover, they'll discover how these systems can be used to understand the evolution of protein families as well as understand and predict the degree to which structural and functional information are shared between relatives in a protein family.\u003c\/p\u003e \u003cp\u003eEdited and authored by leading international experts, \u003ci\u003eProtein Families\u003c\/i\u003e offers new insights into protein families that are important to medical research as well as protein families that help us understand biological systems and key biological processes such as cell signaling and the immune response. The book is divided into three sections:\u003c\/p\u003e \u003cul\u003e \u003cli\u003e\n\u003cb\u003eSection I: Concepts Underlying Protein Family Classification\u003c\/b\u003e reviews the major strategies for identifying homologous proteins and classifying them into families.\u003c\/li\u003e \u003cli\u003e\n\u003cb\u003eSection II: In-Depth Reviews of Protein Families\u003c\/b\u003e focuses on some fascinating super protein families for which we have substantial amounts of sequence, structural and functional data, making it possible to trace the emergence of functionally diverse relatives.\u003c\/li\u003e \u003cli\u003e\n\u003cb\u003eSection III: Review of Protein Families in Important Biological Systems\u003c\/b\u003e examines protein families associated with a particular biological theme, such as the cytoskeleton.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eAll chapters are extensively illustrated, including depictions of evolutionary relationships. References at the end of each chapter guide readers to original research papers and reviews in the field.\u003c\/p\u003e \u003cp\u003eCovering protein family classification systems alongside detailed descriptions of select protein families, this book offers biochemists, molecular biologists, protein scientists, structural biologists, and bioinformaticians new insight into the evolution and nature of proteins.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e  \u003cp\u003e\u003cb\u003eCHRISTINE ORENGO, PhD,\u003c\/b\u003e is Professor of Bioinformatics at University College London. Dr. Orengo's research focuses on protein structure comparison, classification, and analysis. Her group develops the CATH domain family classification and algorithms for predicting protein functions and functional networks.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eALEX BATEMAN, PhD,\u003c\/b\u003e is Senior Investigator at Wellcome Trust Sanger Institute, where he leads the Pfam database project. Dr. Bateman also participates in the European InterPro project, which seeks to merge the annotations from Pfam, PRINTS, Prosite, and other domain databases.\u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e03 February 2014\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9780470624227\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e552\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e33.92\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44310841458828,"sku":"9780470624227","price":151.16,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780470624227_27fae3bf-232e-4795-95a2-c9a8181cadb7.jpg?v=1780174833","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9780470624227","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}