{"product_id":"9780470322826","title":"Targets and Emerging Therapies for Schizophrenia","description":"\u003ch1\u003eTargets and Emerging Therapies for Schizophrenia\u003c\/h1\u003e\u003ch3\u003eJeffrey S. Albert | Michael W. Wood\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eMedical \/ Pharmacology\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003e\u003cb\u003eNew and emerging directions in pharmaceutical research to better treat schizophrenia\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAlthough the dopamine hypothesis has been the cornerstone of schizophrenia therapeutics, it is clear that dopamine-based approaches do not treat all aspects of the disease. Moreover, many schizophrenia patients fail to respond to current antipsychotics. Integrating chemistry, biology, and pharmacology, this book explores emerging directions in pharmaceutical research for drug targeting and discovery in order to find more effective treatments for schizophrenia, one of the most serious and widespread psychiatric diseases.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eTargets and Emerging Therapies for Schizophrenia\u003c\/i\u003e presents the basics of schizophrenia, drug targets for the disease, and potential new drugs and therapeutics. It begins with a discussion of prevalence and etiology. Then, it describes therapies such as dopamine agonists and phosphodiesterase (PDE) inhibitors as well as growing research aimed at addressing untreated symptoms. Next, the authors discuss receptor modulators, inhibitors, and targeting strategies for drug discovery. Both the neurobiological and chemical aspects of all major pharmacological targets are examined.\u003c\/p\u003e \u003cp\u003eWith contributions from an international team of pioneering pharmaceutical researchers, this book compiles the current knowledge in the field, setting the stage for new breakthroughs in the treatment of schizophrenia. \u003ci\u003eTargets and Emerging Therapies for Schizophrenia\u003c\/i\u003e:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eProvides a comprehensive resource for neuro-drug discovery and the development of molecular targets for schizophrenia treatment\u003c\/li\u003e \u003cli\u003eDraws from chemistry, biology, and pharmacology for more effective drug targeting and discovery\u003c\/li\u003e \u003cli\u003eExplores a wide range of receptors and molecular targets, including dopamine, PDEs, and neuropeptides\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eWith \u003ci\u003eTargets and Emerging Therapies for Schizophrenia\u003c\/i\u003e as their guide, drug discovery and development scientists have the information they need to advance their own research so that new, more effective treatments for schizophrenia will soon be a reality.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e  \u003cp\u003e\u003cb\u003eJEFFREY S. ALBERT, PhD,\u003c\/b\u003e is a Project Leader and Head of Lead Generation Chemistry in AstraZeneca's neuroscience department. He has authored or coauthored more than forty publications, mostly focusing on novel therapeutic targets involved in depression, schizophrenia, and Alzheimer's disease and on the development and application of fragment-based lead generation methodologies.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eMICHAEL W. WOOD, PhD,\u003c\/b\u003e is an External Collaborations Director in AstraZeneca's neuroscience unit where he is responsible for coordinating research to deliver novel therapeutics targeting schizophrenia as well as other neuroscience treatments. He has been focused on neuroscience drug discovery research for fifteen years.\u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e10 July 2012\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9780470322826\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e494\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e28.8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44315455783052,"sku":"9780470322826","price":200.66,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780470322826_4b8c1299-1a0c-4aa2-b3da-a7eebf6244fa.jpg?v=1780112750","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9780470322826","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}