{"product_id":"9780470261002","title":"Novel Therapeutic Targets for Antiarrhythmic Drugs","description":"\u003ch1\u003eNovel Therapeutic Targets for Antiarrhythmic Drugs\u003c\/h1\u003e\u003ch3\u003eGeorge Edward Billman\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eMedical \/ Pharmacology\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003e\u003cb\u003ePROFILES POTENTIAL TREATMENT APPROACHES FOR CARDIAC ARRHYTHMIAS\u003c\/b\u003e \u003c\/p\u003e\n\u003cp\u003eCardiac arrhythmias of ventricular origin are responsible for the deaths of nearly half a million Americans each year while atrial fibrillation accounts for about 2.3 million cases per year, a rate that is projected to increase 2.5 fold over the next half century. Effectively managing these cardiac rhythm disorders remains a major challenge for both caregivers and the pharmaceutical industry. Filling a gap in the current literature, \u003ci\u003eNovel Therapeutic Targets for Antiarrhythmic Drugs\u003c\/i\u003e presents the latest treatments for cardiac arrhythmias alongside comprehensive presentations of basic cardiac physiology and pharmacology. \u003c\/p\u003e\n\u003cp\u003eWritten by leading experts in their research areas, this invaluable resource offers both practitioners and researchers a one-stop guide that brings together previously dispersed information. The text consists of four sections: \u003c\/p\u003e\n\u003cul\u003e \u003cli\u003e\n\u003cb\u003eSection One\u003c\/b\u003e comprehensively reviews basic cardiac electrophysiology, the mechanisms responsible for arrhythmias in the setting of ischemia, and basic pharmacology of antiarrhythmic drugs.\u003c\/li\u003e \u003cli\u003e\n\u003cb\u003eSection Two\u003c\/b\u003e addresses safety pharmacology, including the concept of \"repolarization reserve,\" safety challenges, and regulatory issues for the development of novel antiarrhythmic drugs.\u003c\/li\u003e \u003cli\u003e\n\u003cb\u003eSection Three\u003c\/b\u003e describes several novel pharmacological targets for antiarrhythmic drugs, including both ion channel and non-ion channel targets.\u003c\/li\u003e \u003cli\u003e\n\u003cb\u003eSection Four\u003c\/b\u003e describes promising non-pharmacological antiarrhythmic interventions including selective cardiac neural disruption or nerve stimulation, aerobic exercise training, and diet (omega-3 fatty acids).\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eOffering an unparalleled look at the current state and future direction of cardiac arrhythmia treatment, \u003ci\u003eNovel Therapeutic Targets for Antiarrhythmic Drugs\u003c\/i\u003e provides an important resource to advanced students, working researchers, and busy professionals alike.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e  \u003cp\u003e\u003cb\u003eGEORGE EDWARD BILLMAN\u003c\/b\u003e is a professor at The Ohio State University. He is currently an Associate Editor of \u003ci\u003ePharmacology and Therapeutics\u003c\/i\u003e, an Editor of \u003ci\u003eExperimental Physiology\u003c\/i\u003e, and on the editorial boards of Journal of \u003ci\u003eCardiovascular Pharmacology\u003c\/i\u003e and \u003ci\u003eJournal of Applied Physiology\u003c\/i\u003e. Dr. Billman has authored over 125 journal articles and has been an invited speaker at twenty national and international scientific meetings. He wrote the chapter \"Cardiac Sarcolemmal ATP-Sensitive Potassium Channel Antagonists\" in \u003ci\u003eDrug Discovery Handbook\u003c\/i\u003e (Wiley). \u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e07 January 2010\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9780470261002\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e616\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e34.56\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44384208584844,"sku":"9780470261002","price":198.86,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780470261002_162d27a2-13c9-4bf3-922e-121263e7155a.jpg?v=1780111985","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9780470261002","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}